Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network; mutations in human homolog ATP8B1 result in liver disease [Source:SGD;Acc:S000000024]
FUN38, SWA3
Chromosome I: 95,630-99,697 reverse strand.
R64-1-1:BK006935.2
This gene has 1 transcript (splice variant), 382 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
DRS2 | YAL026C_mRNA | 4068 | 1355aa | YAL026C | Protein coding | P39524 | NM_001178171.2 NP_009376.2 |