Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network; mutations in human homolog ATP8B1 result in liver disease [Source:SGD;Acc:S000000024]
FUN38, SWA3
Chromosome I: 95,630-99,697 reverse strand.
R64-1-1:BK006935.2
This gene has 1 transcript (splice variant), 455 orthologues and 4 paralogues.