Protein component of the synaptonemal complex axial elements; involved in chromosome segregation during the first meiotic division; critical for coupling checkpoint signaling to SC formation; promotes interhomolog recombination by phosphorylating Hop1p; also interacts with Mec3p and Ddc1p [Source:SGD;Acc:S000004253]
Chromosome XII: 670,340-672,823 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant) and 19 orthologues.