Delta-1-pyrroline-5-carboxylate dehydrogenase; nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of human homolog ALDH4A1 causes type II hyperprolinemia (HPII), an autosomal recessive inborn error of metabolism; human homolog ALDH4A1 can complement yeast null mutant [Source:SGD;Acc:S000001079]
Chromosome VIII: 181,977-183,704 forward strand.
R64-1-1:BK006934.2
This gene has 1 transcript (splice variant), 457 orthologues and 8 paralogues.