Cytoplasmic tyrosyl-tRNA synthetase; required for cytoplasmic protein synthesis; interacts with positions 34 and 35 of the tRNATyr anticodon; mutations in human ortholog YARS are associated with Charcot-Marie-Tooth (CMT) neuropathies; human ortholog YARS functionally complements the heat sensitivity of a ts allele; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003417]

TTS1, TyrRS

Chromosome VII: 866,336-867,520 reverse strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant) and 66 orthologues.

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