Evolutionarily-conserved 5'-3' exonuclease; component of cytoplasmic processing (P) bodies involved in mRNA decay; also enters the nucleus and positively regulates transcription initiation and elongation; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance; activated by the scavenger decapping enzyme Dcs1p [Source:SGD;Acc:S000003141]

DST2, KEM1, RAR5, SEP1, SKI1

Chromosome VII: 175,527-180,113 reverse strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 176 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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