Saccharomyces cerevisiae (R64-1-1)
Description

Golgi phosphatidylinositol-4-kinase effector and PtdIns4P sensor; interacts with the cytosolic domains of cis and medial glycosyltransferases, and in the PtdIns4P-bound state mediates the targeting of these enzymes to the Golgi; interacts with the catalytic domain of Sac1p, the major cellular PtdIns4P phosphatase, to direct dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; ortholog of human GOLPH3/GPP34/GMx33 [Source:SGD;Acc:S000002780]

Gene Synonyms

API1, MNN3

Location

Chromosome IV: 1,221,112-1,222,149 reverse strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant) and 358 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
VPS74YDR372C_mRNA1038345aaYDR372C
 
Protein coding
Q06385 -Ensembl Canonical