Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; role in DNA catenation/decatenation pathway of chromosome disentangling; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000000065]
BUF2, FUN3, RPA1
Chromosome I: 156,754-158,619 reverse strand.
R64-1-1:BK006935.2
This gene has 1 transcript (splice variant) and 410 orthologues.