Conserved protein of the mitochondrial matrix; performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); ISU1 has a paralog, ISU2, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant [Source:SGD;Acc:S000006056]

NUA1

Chromosome XVI: 297,553-298,050 forward strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 357 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

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