Conserved protein of the mitochondrial matrix; performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); ISU1 has a paralog, ISU2, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant [Source:SGD;Acc:S000006056]
Chromosome XVI: 297,553-298,050 forward strand.
This transcript has 1 exon, is annotated with 8 domains and features, is associated with 16 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YPL135W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ISU1 | YPL135W_mRNA | 498 | 165aa | YPL135W | Protein coding | Q03020 | - | Ensembl Canonical, |