Endosomal Rab family GTPase; required for vacuolar protein sorting, endocytosis and multivesicular body (MVB) biogenesis and sorting; required for localization of the CORVET complex to endosomes; involved in autophagy and ionic stress tolerance; similar to Vps21p and Ypt53p; mammalian Rab5 homolog; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001722]

Chromosome XI: 465,367-466,071 reverse strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 328 orthologues, 12 paralogues and is a member of 1 Ensembl protein family.

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