Endosomal Rab family GTPase; required for vacuolar protein sorting, endocytosis and multivesicular body (MVB) biogenesis and sorting; required for localization of the CORVET complex to endosomes; involved in autophagy and ionic stress tolerance; similar to Vps21p and Ypt53p; mammalian Rab5 homolog; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001722]
Chromosome XI: 465,367-466,071 reverse strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 328 orthologues and 12 paralogues.