Evolutionarily-conserved 5'-3' exonuclease; component of cytoplasmic processing (P) bodies involved in mRNA decay; also enters the nucleus and positively regulates transcription initiation and elongation; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance; activated by the scavenger decapping enzyme Dcs1p [Source:SGD;Acc:S000003141]
DST2, KEM1, RAR5, SEP1, SKI1
Chromosome VII: 175,527-180,113 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 348 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.