Essential protein with distinct roles in two nuclear pore subcomplexes; catalyzes its own proteolytic cleavage in vivo to generate a C-terminal fragment that is a structural component of the Nup84p subcomplex (with roles in NPC biogenesis and localization of genes to the nuclear periphery), and an N-terminal fragment that is one of several FG-nucleoporins within the NPC central core directly responsible for nucleocytoplasmic transport; homologous to human NUP98 [Source:SGD;Acc:S000003060]

RAT10

Chromosome VII: 337,906-341,859 forward strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 47 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.

Show transcript tableHide transcript table