Diphthamide synthetase; catalyzes the last amidation step of diphthamide biosynthesis using ammonium and ATP; evolutionarily conserved in eukaryotes; dph6 mutants exhibit diphthine accumulation and resistance to sordarin, which is indicative of defects in diphthamide formation on EF2; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; DPH6/YLR143W is not an essential gene [Source:SGD;Acc:S000004133]

Chromosome XII: 427,329-429,386 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 359 orthologues and is a member of 1 Ensembl protein family.

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