MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314]

Chromosome XIV: 680,694-685,433 reverse strand.

R64-1-1:BK006947.3

This gene has 1 transcript (splice variant), 328 orthologues, 9 paralogues and is a member of 1 Ensembl protein family.

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