Alpha-1,2-mannosidase; involved in ER-associated protein degradation (ERAD); catalyzes the removal of one mannose residue from a glycosylated protein, converting the modification from Man9GlcNAc to Man8GlcNAc; catalyzes the last step in glycoprotein maturation in the ER and is critical for ER protein degradation [Source:SGD;Acc:S000003892]
Chromosome X: 667,644-669,293 forward strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant), 520 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.