Candida albicans WO-1 (ASM14944v2)

Candida albicans WO-1 Assembly and Gene Annotation

About Candida albicans WO-1 (GCA_000149445)

Candida albicans is an opportunistic pathogenic yeast It is one of the few species of the genus Candida that causes the human infection candidiasis, which results from an overgrowth of the fungus. Candidiasis is for example often observed in HIV-infected patients. C. albicans is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. A mortality rate of 40% has been reported for patients with systemic candidiasis due to C. albicans. By one estimate, invasive candidiasis contracted in a hospital causes 2800 to 11200 deaths yearly in the US.

C. albicans is commonly used as a model organism for biology. It is generally referred to as a dimorphic fungus since it grows both as yeast and filamentous cells. However it has several different morphological phenotypes. C. albicans was for a long time considered an obligate diploid organism without a haploid stage. This is however not the case. Next to a haploid stage C. albicans can also exist in a tetraploid stage. The latter is formed when diploid C. albicans cells mate when they are in the opaque form. The diploid genome size is approximately 29 Mb, and up to 70% of the protein coding genes have not yet been characterized. C. albicans is easily cultured in the lab and can be studied both in vivo and in vitro. Depending on the media different studies can be done as the media influences the morphological state of C. albicans. A special type of medium is CHROMagar™ Candida which can be used to identify different species of candida.

(Text from Wikipedia, the free encyclopaedia.)

Assembly

The assembly presented is the ASM14944v2 assembly submitted to INSDC with the assembly accession GCA_000149445.2.

Annotation

The annotation presented is derived from annotation submitted to INSDC with the assembly accession GCA_000149445.2, with additional non-coding genes derived from Rfam. For more details, please visit INSDC annotation import.

More information

General information about this species can be found in Wikipedia.

Statistics

Summary

AssemblyASM14944v2, INSDC Assembly GCA_000149445.2,
Database version111.1
Golden Path Length14,472,953
Genebuild byBroad Institute
Genebuild methodImport
Data sourceBroad Institute

Gene counts

Coding genes5,752
Non coding genes123
Small non coding genes123
Gene transcripts5,875