Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006384]

Chromosome XVI: 895,961-897,004 forward strand.

This transcript has 1 exon, is annotated with 13 domains and features, is associated with 31 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YPR180W Show transcript tableHide transcript table