Saccharomyces cerevisiae (R64-1-1)
Description

Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) of misfolded proteins; upon autoubiquitination triggers retrotranslocation of misfolded proteins to cytosol for degradation; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; likely plays a general role in targeting proteins that persistently associate with and potentially obstruct the ER-localized translocon [Source:SGD;Acc:S000005373]

Location
About this transcript

This transcript has 1 exon, is annotated with 18 domains and features, is associated with 36 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YOL013C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
HRD1YOL013C_mRNA1656551aaYOL013C
 
Protein coding
Q08109 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 1,656 bps, Translation length: 551 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q08109

Version

YOL013C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD