E2-like enzyme; involved in autophagy and cytoplasm-to-vacuole targeting (Cvt) pathway; plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy and Cvt; interaction with Atg8p regulated by acetylation by NuA4 histone acetyltransferase Esa1p while attenuation of Atg3 acetylation is mediated by histone deacetylase Rpd3p; Atg12p-Atg5p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site [Source:SGD;Acc:S000005290]
Chromosome XIV: 639,182-640,114 reverse strand.
This transcript has 1 exon, is annotated with 15 domains and features, is associated with 20 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YNR007C Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ATG3 | YNR007C_mRNA | 933 | 310aa | YNR007C | Protein coding | P40344 | - | Ensembl Canonical, |