DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, error-prone translesion synthesis; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; forms nuclear foci upon DNA replication stress; associates with native telomeres, cooperates with homologous recombination in senescent cells; human homolog HLTF can complement yeast null mutant [Source:SGD;Acc:S000004022]

Chromosome XII: 204,991-208,500 forward strand.

This transcript has 1 exon, is annotated with 32 domains and features and is associated with 101 variant alleles.

This transcript is a product of gene YLR032W Show transcript tableHide transcript table