Saccharomyces cerevisiae (R64-1-1)
Description

Component of U4/U6-U5 snRNP complex; involved in second catalytic step of splicing; participates in spliceosomal assembly through its interaction with U1 snRNA; largest and most evolutionarily conserved protein of the spliceosome; mutations in human ortholog, PRPF8, cause Retinitis pigmentosa and missplicing in Myelodysplastic syndrome; mouse ortholog interacts with androgen receptor and may have a role in prostate cancer [Source:SGD;Acc:S000001208]

Location
About this transcript

This transcript has 1 exon, is annotated with 30 domains and features, is associated with 130 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YHR165C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PRP8YHR165C_mRNA72422413aaYHR165C
 
Protein coding
P33334 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 7,242 bps, Translation length: 2,413 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P33334

Version

YHR165C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD