Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; role in proteolysis of spindle positioning protein Kar9, DNA repair proteins Rad52p and Rad57p; stimulated by SUMO-modified substrates; contains a C-terminal RING domain; forms nuclear foci upon DNA replication stress; required for maintenance of genome integrity like human ortholog RNF [Source:SGD;Acc:S000000918]
Chromosome V: 395,348-396,172 reverse strand.
This transcript has 1 exon, is annotated with 19 domains and features, is associated with 30 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YER116C Show transcript tableHide transcript table