Saccharomyces cerevisiae (R64-1-1)
Description

E3 ubiquitin ligase; forms heterodimer with Rad6p to regulate K63 polyubiquitination in response to oxidative stress and to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control; interacts with RNA-binding protein Npl3p, linking histone ubiquitination to mRNA processing; Bre1p-dependent histone ubiquitination promotes pre-mRNA splicing [Source:SGD;Acc:S000002232]

Location
About this transcript

This transcript has 1 exon, is annotated with 22 domains and features, is associated with 20 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YDL074C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
BRE1YDL074C_mRNA2103700aaYDL074C
 
Protein coding
Q07457 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 2,103 bps, Translation length: 700 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q07457

Version

YDL074C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD