Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication [Source:SGD;Acc:S000006358]
Chromosome XVI: 834,565-835,212 forward strand.
This transcript has 1 exon, is annotated with 23 domains and features, is associated with 32 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YPR154W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
PIN3 | YPR154W_mRNA | 648 | 215aa | YPR154W | Protein coding | Q06449 | - | Ensembl Canonical, |