Involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; serves at interface between dynein's ATPase site and its microtubule binding stalk, causing individual dynein motors to remain attached to microtubules for long periods; synthetic lethal with bni1; homolog of human LIS1, mutations in which cause the severe brain disorder lissencephaly [Source:SGD;Acc:S000005795]

Chromosome XV: 826,385-827,869 forward strand.

This transcript has 1 exon, is annotated with 29 domains and features, is associated with 26 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YOR269W Show transcript tableHide transcript table