SUMO E3 ligase; catalyzes sumoylation of Yku70p/80p and Sir4p promoting telomere anchoring to the nuclear envelope and regulating telomerase activity; DNA-bound form catalyzes a DNA-damaged triggered sumoylation wave resulting in multisite modification of several DNA repair proteins, enhancing interactions between these proteins and accelerating repair; sumoylates Cse4p, a prerequisite for STUbL-mediated Ub-dependent degradation; role in telomere length maintenance [Source:SGD;Acc:S000005682]

Chromosome XV: 628,360-630,540 reverse strand.

This transcript has 1 exon, is annotated with 19 domains and features, is associated with 46 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YOR156C Show transcript tableHide transcript table