WD repeat protein required for ubiquitin-mediated protein degradation; ubiquitin binding cofactor that complexes with Cdc48p; required for ribophagy; controls cellular ubiquitin concentration; promotes efficient NHEJ in postdiauxic/stationary phase; facilitates N-terminus-dependent proteolysis of centromeric histone H3 (Cse4p) for faithful chromosome segregation; protein increases in abundance and relocalizes from nucleus to nuclear periphery upon DNA replication stress [Source:SGD;Acc:S000001696]

Chromosome XI: 31,960-34,107 reverse strand.

This transcript has 1 exon, is annotated with 41 domains and features, is associated with 42 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YKL213C Show transcript tableHide transcript table