Membrane-embedded ubiquitin-protein ligase; ER and inner nuclear membrane localized RING-CH domain E3 ligase involved in ER-associated protein degradation (ERAD); targets misfolded cytosolic/nucleoplasmic domains of soluble and membrane embedded proteins (ERAD-C) and a transmembrane domain containing substrate (ERAD-M), Sbh2p; C-terminal element (CTE), conserved in human ortholog MARCH10/TEB4, determines substrate selectivity [Source:SGD;Acc:S000001292]

Chromosome IX: 296,050-300,009 reverse strand.

This transcript has 1 exon, is annotated with 31 domains and features, is associated with 69 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YIL030C Show transcript tableHide transcript table