Nuclear protein with a role in protein quality control; localizes to the intranuclear quality control compartment (INQ) in response to proteasome inhibition or DNA replication stress; INQ likely sequesters proteins involved in DNA metabolism for degradation or re-folding; DNA-binding protein with preference for UV-damaged DNA; contains three WD domains (WD-40 repeat); human ortholog WDR76 also exhibits perinuclear localization under similar stress conditions [Source:SGD;Acc:S000002315]
Chromosome IV: 174,918-176,486 forward strand.
This transcript has 1 exon, is annotated with 17 domains and features, is associated with 46 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDL156W Show transcript tableHide transcript table