Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex; role in Ub-mediated degradation of histone variant Cse4p preventing mislocalization to euchromatin; role in proteolysis of spindle positioning protein Kar9p, and DNA repair proteins Rad52p and Rad57p; forms SUMO-dependent nuclear foci, including DNA repair centers; contains a RING domain and two SIM motifs; associates with the centromere; required for maintenance of genome integrity like human ortholog RNF4 [Source:SGD;Acc:S000002171]

Chromosome IV: 429,067-430,926 forward strand.

This transcript has 1 exon, is annotated with 19 domains and features and is associated with 27 variant alleles.

This transcript is a product of gene YDL013W Show transcript tableHide transcript table