Mitochondrial protein required for iron-sulfur protein synthesis; performs scaffolding function during Fe/S cluster assembly; involved in Fe-S cluster assembly for both mitochondrial and cytosolic proteins; protein abundance increases under DNA replication stress; ISU2 has a paralog, ISU1, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant [Source:SGD;Acc:S000005752]

Chromosome XV: 761,614-762,084 reverse strand.

This transcript has 1 exon, is annotated with 15 domains and features and is associated with 13 variant alleles.

This transcript is a product of gene YOR226C Show transcript tableHide transcript table