DDHD domain-containing phospholipase A1; mitochondrial matrix enzyme with sn-1-specific activity, hydrolyzing cardiolipin, PE, PC, PG and PA; implicated in remodeling of mitochondrial phospholipids; antagonistically regulated by Aft1p and Aft2p; in humans, mutations in DDHD1 and DDHD2 genes cause specific types of hereditary spastic paraplegia, while DDL1-defective yeast share similar phenotypes such as mitochondrial dysfunction and defects in lipid metabolism [Source:SGD;Acc:S000005548]

Chromosome XV: 373,710-375,857 reverse strand.

This transcript has 1 exon, is annotated with 14 domains and features, is associated with 52 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YOR022C Show transcript tableHide transcript table