GTPase-activating protein of the Ras superfamily; acts primarily on Sec4p, localizes to the bud site and bud tip; msb3 msb4 double mutation causes defects in secretion and actin organization; similar to the TBC-domain Tre2 oncogene; MSB4 has a paralog, MSB3, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null mutant [Source:SGD;Acc:S000005472]
Chromosome XV: 106,710-108,188 forward strand.
This transcript has 1 exon, is annotated with 12 domains and features, is associated with 25 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YOL112W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
MSB4 | YOL112W_mRNA | 1479 | 492aa | YOL112W | Protein coding | Q12317 | - | Ensembl Canonical, |