Assembly factor for the eIF2 translation initiation factor complex; regulates translational initiation; conserved residues of this ATP-Grasp protein that bind to ATP-Mg2+ in the pombe ortholog are required for complex assembly in budding yeast; interaction with eIF2 subunit Gcd11p facilitates complex assembly and activity; required for the START transition and timely progression through G2; regulated by nutrient availability; human ortholog complements the yeast mutant [Source:SGD;Acc:S000004205]
Chromosome XII: 570,776-571,858 reverse strand.
This transcript has 1 exon, is annotated with 6 domains and features and is associated with 33 variant alleles.
This transcript is a product of gene YLR215C Show transcript tableHide transcript table