Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx2p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases iunder DNA replication stress; TRX1 has a paralog, TRX2, that arose from the whole genome duplication [Source:SGD;Acc:S000004033]

Chromosome XII: 231,702-232,013 reverse strand.

This transcript has 1 exon, is annotated with 24 domains and features, is associated with 17 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YLR043C Show transcript tableHide transcript table