cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]
Chromosome X: 109,966-111,159 reverse strand.
This transcript has 1 exon, is annotated with 17 domains and features and is associated with 23 variant alleles.
This transcript is a product of gene YJL164C Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
TPK1 | YJL164C_mRNA | 1194 | 397aa | YJL164C | Protein coding | P06244 | - | Ensembl Canonical, |