Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; with Grx3p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; mutant has increased aneuploidy tolerance; transcription regulated by Yap5p; GRX4 has a paralog, GRX3, that arose from the whole genome duplication [Source:SGD;Acc:S000000976]

Chromosome V: 538,434-539,168 reverse strand.

This transcript has 1 exon, is annotated with 16 domains and features, is associated with 21 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YER174C Show transcript tableHide transcript table