Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region; inhibition of Tpi1p activity by PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human homolog TPI1 causes a rare autosomal disease; human TPI1 can complement yeast null mutant [Source:SGD;Acc:S000002457]

Chromosome IV: 555,726-556,472 reverse strand.

This transcript has 1 exon, is annotated with 23 domains and features, is associated with 11 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YDR050C Show transcript tableHide transcript table