Cytoplasmic DEAD-box helicase, stimulates mRNA decapping; coordinates distinct steps in mRNA function and decay, interacting with both decapping and deadenylase complexes; role in translational repression, mRNA decay, and possibly mRNA export; interacts and cooperates with Ngr1p to promote specific mRNA decay; ATP- and RNA-bound form promotes processing body (PB) assembly, while ATPase stimulation by Not1p promotes PB disassembly; forms cytoplasmic foci on replication stress [Source:SGD;Acc:S000002319]

Chromosome IV: 170,410-171,930 reverse strand.

This transcript has 1 exon, is annotated with 27 domains and features, is associated with 27 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YDL160C Show transcript tableHide transcript table