Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]
Chromosome IV: 400,997-403,291 reverse strand.
This transcript has 1 exon, is annotated with 24 domains and features, is associated with 32 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDL028C Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
MPS1 | YDL028C_mRNA | 2295 | 764aa | YDL028C | Protein coding | P54199 | - | Ensembl Canonical, |