NAD-dependent glycerol-3-phosphate dehydrogenase; key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; protein abundance increases in response to DNA replication stress; constitutively inactivated via phosphorylation by the protein kinases Ypk1p and Ypk2p, dephosphorylation increases catalytic activity; forms a heterodimer with Pnc1p to facilitate its peroxisomal import [Source:SGD;Acc:S000002180]
Chromosome IV: 411,825-413,000 forward strand.
This transcript has 1 exon, is annotated with 27 domains and features, is associated with 21 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDL022W Show transcript tableHide transcript table