Methylesterase performing penultimate step of diphthamide biosynthesis; hydrolyzes methylated diphthine to produce diphthine and allows Dph6-catalyzed amidation reaction to occur; deletion leads to resistance to sordarin and accumulation of methylatediphthine; WD40 domain-containing protein; involved in endosomal recycling; forms complex with Rtt10p that functions in retromer-mediated pathway for recycling internalized cell-surface proteins [Source:SGD;Acc:S000000450]

Chromosome II: 711,591-712,754 forward strand.

This transcript has 1 exon, is annotated with 12 domains and features and is associated with 39 variant alleles.

This transcript is a product of gene YBR246W Show transcript tableHide transcript table