Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]

Chromosome II: 505,668-512,774 forward strand.

This transcript has 1 exon, is annotated with 22 domains and features, is associated with 98 variant alleles and maps to 92 oligo probes.

This transcript is a product of gene YBR136W Show transcript tableHide transcript table