5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS4 has a paralog, PRS2, that arose from the whole genome duplication; a missense mutation in the conserved residue R196 of its human homolog PRPS1 is pathogenic [Source:SGD;Acc:S000000164]

Chromosome II: 92,414-93,394 forward strand.

This transcript has 1 exon, is annotated with 18 domains and features, is associated with 25 variant alleles and maps to 28 oligo probes.

This transcript is a product of gene YBL068W Show transcript tableHide transcript table