S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C at wobble position in response to hydrogen peroxide, causing selective translation of mRNA from genes enriched in TTG codon; loss of NCL1 confers hypersensitivity to oxidative stress; similar to Nop2p and human proliferation associated nucleolar protein p120 [Source:SGD;Acc:S000000120]

Chromosome II: 172,534-174,588 forward strand.

This transcript has 1 exon, is annotated with 23 domains and features, is associated with 41 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YBL024W Show transcript tableHide transcript table