Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain [Source:SGD;Acc:S000005991]

Chromosome XVI: 420,948-422,786 forward strand.

This transcript has 1 exon, is annotated with 23 domains and features, is associated with 17 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YPL070W Show transcript tableHide transcript table