Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS [Source:SGD;Acc:S000005648]

Chromosome XV: 552,298-552,887 reverse strand.

This transcript has 2 exons, is annotated with 23 domains and features, is associated with 14 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YOR122C Show transcript tableHide transcript table