Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins [Source:SGD;Acc:S000004601]
Chromosome XIII: 7,244-8,383 forward strand.
This transcript has 1 exon, is annotated with 9 domains and features, is associated with 97 variant alleles and maps to 72 oligo probes.
This transcript is a product of gene YML132W Show transcript tableHide transcript table